bonvoyage is a tool for the detection of alternative splicing in RNA-seq data. The bonvoyage algorithm uses the outrigger de novo splice graph method and a Bayesian approach for modality assignment. It can also show changes in modalities using non-negative matrix factorization.
Genetic variation; RNA-seq; RNA splicing
Song Y, Botvinnik OB, Lovci MT, Kakaradov B, Liu P, Xu JL, Yeo GW "Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation." Mol Cell. 2017 Jul 6;67(1):148-161.e5. 2017 Jun 29. https://doi.org/10.1016/j.molcel.2017.06.003
PMID: 28673540
PMCID: PMC5540791
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