dropEst is a pipeline tool to estimate molecular counts in droplet-based single-cell RNA-seq (scRNA-seq) data. The dropEst package correct barcodes, classifies cell quality, computes diagnostic information about the libraries, corrects sequencing errors, and composition bias.
Gene expression; RNA-Seq
Petukhov V, Guo J, Baryawno N, Severe N, Scadden DT, Samsonova MG, Kharchenko PV "dropEst: Pipeline for Accurate Estimation of Molecular Counts in Droplet-Based Single-Cell RNA-seq Experiments" Genome Biol. 2018 Jun 19;19(1):78. https://doi.org/10.1186/s13059-018-1449-6
PMID: 29921301
PMCID: PMC6010209
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