f-scLVM (factorial single-cell latent variable model) implemented in the slalom package to estimate factors, refine gene set annotations to assess and model confounding factors contributing to cell-cell variability.
Gene expression; RNA-seq; Annotation
Buettner F, Pratanwanich N, McCarthy DJ, Marioni JC, Stegle O "f-scLVM: scalable and versatile factor analysis for single-cell RNA-seq." Genome Biol. 2017 Nov 7;18(1):212. https://doi.org/10.1186/s13059-017-1334-8
PMID: 29115968
PMCID: PMC5674756
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