scVEGs is a tool for analysis of differentially expressed genes in single-cell RNA-seq data. The scVEGs algorithm uses a gene expression variation model (GEVM) and makes use of the relation between the coefficient of variation (CV) and mean expression level to adjust for over-dispersion and compute statistical significance.
RNA-seq; Gene expression
Chen HI, Jin Y, Huang Y, Chen Y "Detection of high variability in gene expression from single-cell RNA-seq profiling." BMC Genomics. 2016 Aug 22;17 Suppl 7:508. https://doi.org/10.1186/s12864-016-2897-6
PMID: 27556924
PMCID: PMC5001205
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