singlecell_pnm is the Jupyter notebook code for single-cell alternative splicing. This is the code for the paper by Song and Botvinnik, et al., Molecular Cell (2017), investigating alternative splicing in single cells in neurodegenerative disease.
Sequencing; RNA-seq; Transcriptomics
Song Y, Botvinnik OB, Lovci MT, Kakaradov B, Liu P, Xu JL, Yeo GW "Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation." Mol Cell. 2017 Jul 6;67(1):148-161.e5. 2017 Jun 29. https://doi.org/10.1016/j.molcel.2017.06.003
PMID: 28673540
PMCID: PMC5540791
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