FALCON is a tool for de novo assembly of long PacBio reads and it is an improved version of its predecessor HGAP. Unlike HGAP, it is a diploid-aware assembler that is better suited to assemble larger genomes. Users should look into FALCON-Unzip if they wish to phase the assembly as well.
Sequence assembly
Chin CS, Peluso P, Sedlazeck FJ, Nattestad M, Concepcion GT, Clum A, Dunn C, O'Malley R, Figueroa-Balderas R, Morales-Cruz A, Cramer GR, Delledonne M, Luo C, Ecker JR, Cantu D, Rank DR, Schatz MC "Phased diploid genome assembly with single-molecule real-time sequencing." Nat Methods. 2016 Dec;13(12):1050-1054. 17. https://doi.org/10.1038/nmeth.4035
PMID: 27749838
PMCID: PMC5503144
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