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HINGE
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HINGE

HINGE is a tool for de novo genome assembly that addresses the challenge of using error prone long reads. It combines error tolerance feature of Overlap-Layout-Consensus and repeat resolution of de Bruijn graph assembler. Additionally, HINGE produces visually interpretable assembly graph.



HINGE

HINGE is a tool for de novo genome assembly that addresses the challenge of using error prone long reads. It combines error tolerance feature of Overlap-Layout-Consensus and repeat resolution of de Bruijn graph assembler. Additionally, HINGE produces visually interpretable assembly graph.

Topic

Sequence assembly

Details

  • Operation: Sequence assembly; De novo assembly
  • Software interface: command-line user interface
  • Language: C
  • Operating system: Mac OS X, Linux
  • License: Not stated
    • Cost: Free
  • Version name: -
  • Credit: Shoudan Liang and Jason Chin of Pacific Biosciences
  • Contact: courtade _at_ eecs.berkeley.edu; dntse _at_ stanford.edu
  • Collection: -

Publications

Kamath GM, Shomorony I, Xia F, Courtade TA, Tse DN "HINGE: long-read assembly achieves optimal repeat resolution." Genome Res. 2017 May;27(5):747-756. https://doi.org/10.1101/gr.216465.116
PMID: 28320918
PMCID: PMC5411769


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