LoRDEC is an error correction tool for long reads e.g. PacBio, using highly accurate short reads. This tool can be used prior to de novo assembly as the indel errors in long reads complicate assembly. The algorithm implements de Bruijn graph of short reads and looks for corrective sequence in each potentially erroneous region in long reads.
Sequences assembly
Salmela L, Rivals E "LoRDEC: accurate and efficient long read error correction." Bioinformatics 2014; 30(24):3506-14 https://doi.org/10.1093/bioinformatics/btu538
PMID: 25165095
PMCID: PMC4253826
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