SOAPdenovo is a tool for de novo genome assembly using entirely Illumina short reads. The algorithm implements error correction, de Bruijn graph construction, tip removal, repeat resolution, bubbles merging, contig linkage graph and scaffolding. This tool has a modularized design for each assembly step and has been proven to work on human genomes.
Sequence assembly
Li R, Zhu H, Ruan J, Qian W, Fang X, Shi Z, Li Y, Li S, Shan G, Kristiansen K, Li S, Yang H, Wang J, Wang J "De novo assembly of human genomes with massively parallel short read sequencing." Genome Res. 2010; 20(2):265-72 https://doi.org/10.1101/gr.097261.109
PMID: 20019144
PMCID: PMC2813482
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