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laSV is a tool for detecting structural variants (SVs) from paired-end sequenced data at single base pair resolution. It implements a local assembly algorithm that goes through the step of constructing and storing de Bruijn graph before arriving at SVs. This tool can be useful to those who study cancers and wish to identify SVs that are different among individuals.


Sequence assembly



Zhuang J, Weng Z "Local sequence assembly reveals a high-resolution profile of somatic structural variations in 97 cancer genomes." Nucleic Acids Res. 2015 Sep 30;43(17):8146-56. Aug 17.
PMID: 26283183
PMCID: PMC4787836

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