An R tool to reconstruct full-length B-cell-receptor (BCR) sequences from paired-end or single-end single-cell RNA-seq data. BraCeR is an extension of the TraCeR pipeline and can also determine clonality, estimate somatic hypermutations (SHMs), isotype switching, and create resource files for analyses of additional species. The default version is human and mice.
Cell biology; RNA-seq; Immunoproteins, genes and antigens
Lindeman I, Emerton G, Mamanova L, Snir O, Polanski K, Qiao SW, Sollid LM, Teichmann SA, Stubbington MJT "BraCeR: B-cell-receptor reconstruction and clonality inference from single-cell RNA-seq." Nat Methods. 2018 Aug;15(8):563-565. https://doi.org/10.1038/s41592-018-0082-3
PMID: 30065371
If you find errors, please report here.
SECTIONS
TutorialsFind thousands of Bioinformatics and Life Science software tools and databases in the newly launched
Ads