An R tool to reconstruct T-cell receptor genes from single-cell RNA-seq data. The TraCeR algorithm can also identify cells containing identical T-cell receptors to determine clonally propagated cells.
Cell biology; RNA-seq; Immunoproteins, genes and antigens
Lindeman I, Emerton G, Mamanova L, Snir O, Polanski K, Qiao SW, Sollid LM, Teichmann SA, Stubbington MJT "BraCeR: B-cell-receptor reconstruction and clonality inference from single-cell RNA-seq." Nat Methods. 2018 Aug;15(8):563-565. https://doi.org/10.1038/s41592-018-0082-3
PMID: 30065371
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