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Oases

Oases

Oases is a tool for assembling de novo transcriptomes using short RNA-seq reads. The Oases algorithm uses dynamic error removal in the prediction of full-length transcripts, and it can handle a wide range of expression values and the absence of alternative iso-forms. Requires Velvet 1.2.08 or higher (see links).

Topic

Transcriptomics; Whole genome sequencing; RNA-Seq; Sequence assembly

Details

  • Operation: De-novo assembly; Read mapping; Gene expression analysis; RNA-Seq analysis
  • Software interface: Command-line user interface
  • Language: C
  • Operating system: Linux
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: 0.2.08
  • Maturity: Mature
  • Credit: International Max Planck Research School for Computational Biology and Scientific Computing, the European Molecular Biology Laboratory (EMBL), The National Human Genome Research Institute (NHGRI); ENCODE, DAC.
  • Contact: Marcel Schulz marcel.schulz _at_ molgen.mpg.de | Daniel Zerbino dzerbino _at_ soe.ucsc.edu
  • Collection: -

Publications

Schulz MH, Zerbino DR, Vingron M, Birney E "Oases: robust de novo RNA-seq assembly across the dynamic range of expression levels." Bioinformatics. 2012 Apr 15;28(8):1086-92. Epub 2012 Feb 24. https://doi.org/10.1093/bioinformatics/bts094
PMID: 22368243
PMCID: PMC3324515


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