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IgDiscover

IgDiscover

IgDiscover tool is for the analyzes of antibody repertoires. IgDiscover algorithm identifies new V genes, heavy chains, kappa, and lambda light chains to discover VH, VK, and VL genes.

Topic

Nucleic acid structure analysis

Details

  • Operation: Homology-based gene prediction; Gene expression profiling
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Linux; Mac OS X
  • License: The MIT License
  • Cost: Free
  • Version name: 0.12.3
  • Credit: NIH, the International AIDS Vaccine Initiative (IAVI), Karolinska Institutet KID grant, the Knut and Alice Wallenberg Foundation to the Wallenberg Advanced Bioinformatics Infrastructure.
  • Contact: igdiscover _at_ googlegroups.com
  • Collection: -

Publications

Corcoran MM, Phad GE, Vázquez Bernat, Stahl-Hennig C, Sumida N, Persson MA, Martin M, Karlsson Hedestam GB "Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity." Nat Commun 2016 https://doi.org/10.1038/ncomms13642
PMID: 27995928
PMCID: PMC5187446


Download and documentation




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