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eShadow is a web-based tool for comparative nucleotide sequence analysis. The eShadow algorithm uses two statistical methods. And can train an underlying Hidden Markov Model to predict functional sequences.


Sequence analysis; Phylogenetics; Computational biology


  • Operation: Sequence analysis
  • Software interface: Web user interface
  • Language: -
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Maturity: Mature
  • Credit: U.S. Department of Energy by the University of California, Lawrence Livermore National Laboratory, Lawrence Berkeley National Laboratory Contract.
  • Contact: ovcharen _at_
  • Collection: -


Ovcharenko I, Boffelli D, Loots GG "eShadow: a tool for comparing closely related sequences." Genome Res. 2004; 14(6):1191-8
PMID: 15173121
PMCID: PMC419798

Download and documentation

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