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ADMIRE is a tool for identification repeated copy number variation (CNV). The ADMIRE algorithm identifies recurrent, multi-scale events, and uses multi-scale Gaussian smoothing. The ADMIRE algorithm does not require segmentation nor calling for the input dataset because it controls the false recovery analytically. The output of the algorithm is a single profile of significant events selected from the scales.


Genetics; Genetic variation


  • Operation: Variant detection; Copy number estimation
  • Software interface: Command-line user interface
  • Language: Matlab
  • Operating system: Mac OS X, Linux
  • License: Not stated
  • Cost: Free
  • Version name: 1.2
  • Maturity: Stable
  • Credit: BioRange programme of the Netherlands Bioinformatics Centre (NBIC), the Netherlands Genomics Initiative (NGI), the Delft University of Technology, The Netherlands.
  • Contact: Lodewyk F.A. Wessels l.wessels _at_
  • Collection: -


van Dyk E, Reinders MJ, Wessels LF "A scale-space method for detecting recurrent DNA copy number changes with analytical false discovery rate control." Nucleic Acids Res. 2013 May;41(9):e100.
PMID: 23476020
PMCID: PMC3643574

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