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Accurity is a software tool for inferring tumor cell ploidy, tumor purity, and absolute allelic copy numbers for somatic copy number alterations in whole-genome sequencing (WGS) data.


Genetics; Whole genome sequencing; DNA structural variation; Oncology


  • Operation: Polymorphism detection; Sequence analysis; Structural variation detection; Copy number detection
  • Input: BAM
  • Output: TSV
  • Software interface: Command-line user interface
  • Language: C++;Rust
  • Operating system: Mac OS X, Linux
  • License: Other
  • Cost: Free for non-commercial purposes
  • Version name: -
  • Credit: China Thousand-Talent program, Chinese Academy of Sciences Hundred-Talent program Y6G7011018, Strategic Priority Research Program of the Chinese Academy of Sciences.
  • Contact: Huang YS yuhuang _at_
  • Collection: -


Luo Z, Fan X, Su Y, Huang YS "Accurity: accurate tumor purity and ploidy inference from tumor-normal WGS data by jointly modelling somatic copy number alterations and heterozygous germline single-nucleotide-variants." Bioinformatics. 2018 Jun 15;34(12):2004-2011.
PMID: 29385401

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