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BACOM

BACOM

BACOM (Bayesian Analysis of COpy number Mixtures) is a package that contains a pipeline for copy number variation (CNV) analysis in heterogeneous cancer cell sample data. BACOM also estimates deletions and tissue contamination. See also links for BACOM2.0.
Alternative name: bacomR (an R interface for BACOM Java version).

Topic

Genetics; Oncology; Statistics and probability; Genetic variation

Details

  • Operation: Statistical inference; variation detection
  • Software interface: Graphical user interface; command-line user interface
  • Language: Java;R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: The 3-Clause BSD License
  • Cost: Free
  • Version name: 1.0
  • Maturity: Legacy
  • Credit: The National Institutes of Health (NIH).
  • Contact: Yue Wang yuewang _at_ vt.edu
  • Collection: -

Publications

Yu G, Zhang B, Bova GS, Xu J, Shih IeM, Wang Y "BACOM: in silico detection of genomic deletion types and correction of normal cell contamination in copy number data." Bioinformatics. 2011 Jun 1;27(11):1473-80. Epub 2011 Apr 15. https://doi.org/10.1093/bioinformatics/btr183
PMID: 21498400
PMCID: PMC3102226


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