For better experience, turn on JavaScript!

CLImAT-HET
Home » Tools » CNV Tools » CLImAT-HET

CLImAT-HET

CLImAT-HET is a tool for the detection of subclonal copy number variation (CNV) and loss of heterozygosity in tumor samples. The CLImAT-HET algorithm uses whole-genome sequencing (WGS) data and a factorial hidden Markov model.



CLImAT-HET

CLImAT-HET is a tool for the detection of subclonal copy number variation (CNV) and loss of heterozygosity in tumor samples. The CLImAT-HET algorithm uses whole-genome sequencing (WGS) data and a factorial hidden Markov model.

Topic

Genetics; Whole genome sequencing; DNA structural variation; Oncology

Details

  • Operation: Polymorphism detection; Sequence analysis; Structural variation detection
  • Software interface: Command-line user interface
  • Language: C;Matlab
  • Operating system: Microsoft Windows, Mac OS X, Linux
  • License: GNU GPL v2
    • Cost: Free
  • Version name: 1.0.0
  • Credit: National Natural Science Foundation of China
  • Contact: Zhenhua Yu yzh163 _at_ mail.ustc.edu.cn
  • Collection: -

Publications

Yu Z, Li A, Wang M "CLImAT-HET: detecting subclonal copy number alterations and loss of heterozygosity in heterogeneous tumor samples from whole-genome sequencing data." BMC Med Genomics. 2017 Mar 15;10(1):15. https://doi.org/10.1186/s12920-017-0255-4
PMID: 28298214
PMCID: PMC5351278


Download and documentation







If you find errors, please report here.

SECTIONS

Tutorials
In-house software
Blog
News
Find Jobs
History
Definition of Bioinformatics
ENCYCLOPEDIA
COVID-19
⚬ Timeline of outbreak
⚬ Blog
⚬ Scientific Facts
⚬ Daily statistics
⚬ News


TOOLS


1. SNP Tools
2. GWAS Tools
3. Genotype Imputation Tools
4. MSA tools
5. CNV tools
6. WGA tools
7. RNA-seq tools
8. Proteomics Tools
9. Nucleic Acid Structure Analysis Tools
10. Nucleic Acid Sequence Analysis Tools
11. Sequence Logo Tools
12. In-house Software Tools

Find thousands of Bioinformatics and Life Science software tools and databases in the newly launched




Ads