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CNOGpro is an R package for detection and identification of copy number variation (CNV) specifically in prokaryotic whole-genome sequencing data. The tool uses Hidden Markov Model (HMM) and bootstrapping.


Model organisms; Genetic variation


  • Operation: Copy number estimation
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU GPL v2
  • Cost: Free
  • Version name: 1.1
  • Maturity: Mature
  • Credit: Norwegian University of Life Sciences (NMBU).
  • Contact: ola.brynildsrud _at_
  • Collection: -


Brynildsrud O, Snipen LG1, Bohlin J "CNOGpro: detection and quantification of CNVs in prokaryotic whole-genome sequencing data." Bioinformatics. 2015 Jun 1;31(11):1708-15.
PMID: 25644268

Download and documentation

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