CNVrd2 is a command-line tool for the detection of copy number variation (CNV). The algorithm uses a linear regression model and a Bayesian normal mixture model for estimating individual copy number counts.
Whole genome sequencing; DNA polymorphism
Nguyen HT, Merriman TR, Black MA "The CNVrd2 package: measurement of copy number at complex loci using high-throughput sequencing data." Front Genet. 2014 Aug 1;5:248. https://doi.org/10.3389/fgene.2014.00248
PMID: 25136349
PMCID: PMC4117933
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PMID: 25633503
PMCID: PMC4509590
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J. "Bioconductor: open software development for computational biology and bioinformatics." Genome Biol. 2004;5(10):R80. Epub 2004 Sep 15. https://doi.org/10.1186/gb-2004-5-10-r80
PMID: 15461798
PMCID: PMC545600
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