DBS

DBS (Deviation Binary Segmentation) is a tool for segmenting copy number variable (CNV) genomic locations. The inspiration for the DBS algorithm originates from the segmentation method based on the circular binary segmentation method. It uses a point-by-point model calculation coupled with a binary search algorithm with heuristics derived from the Central Limit Theorem. DBS can measure the change-point amplitude of mean values of two neighboring segments at a breakpoint.