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DNACopyNumber is a tool for detection of copy number variation (CNV). The DNACopyNumber algorithm us based on penalized least squares regression and bootstrapping to estimate the statistical significance.


Genetics; DNA structural variation; Oncology


  • Operation: Polymorphism detection; Structural variation detection
  • Software interface: Command-line user interface
  • Language: -
  • Operating system: Linux
  • License: Not stated
  • Cost: -
  • Version name: -
  • Maturity: Legacy
  • Credit: National Institutes of Health (NIH), National Science Foundation (NSF).
  • Contact: Hongyu Zhao hongyu.zhao _at_
  • Collection: -


Huang T, Wu B, Lizardi P, Zhao H "Detection of DNA copy number alterations using penalized least squares regression." Bioinformatics. 2005 Oct 15;21(20):3811-7. Epub 2005 Aug 30.
PMID: 16131523

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