DNACopyNumber is a tool for detection of copy number variation (CNV). The DNACopyNumber algorithm us based on penalized least squares regression and bootstrapping to estimate the statistical significance.
Genetics; DNA structural variation; Oncology
Huang T, Wu B, Lizardi P, Zhao H "Detection of DNA copy number alterations using penalized least squares regression." Bioinformatics. 2005 Oct 15;21(20):3811-7. Epub 2005 Aug 30. https://doi.org/10.1093/bioinformatics/bti646
PMID: 16131523
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