MGP-HMM is a tool for detecting copy number variation (CNV). The MGP-HMM algorithm uses a hidden Markov Model (HMM) to discriminate copies from duplicated in tandem from other repeats and, also, a Poisson distribution to model the read depth and to estimate CNV lengths.
Genetics; Genetic variation
Malekpour SA, Pezeshk H, Sadeghi M "MGP-HMM: Detecting genome-wide CNVs using an HMM for modeling mate pair insertion sizes and read counts." Math Biosci. 2016 Sep;279:53-62. 16. https://doi.org/10.1016/j.mbs.2016.07.006
PMID: 27424951
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