PyLOH is a tool for detecting copy number variation (CNV) and loss of heterozygosity in cancer genomes. The algorithm uses a unified probabilistic framework.
Oncology; DNA; DNA polymorphism
Li Y, Xie X "Deconvolving tumor purity and ploidy by integrating copy number alterations and loss of heterozygosity." Bioinformatics. 2014 Aug 1;30(15):2121-9. https://doi.org/10.1093/bioinformatics/btu174
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