STAC is a tool for testing the significance of DNA copy number variation (CNV). The STAC method uses two separate statistics, and it computes the final P-values by multiple testing corrected permutations.
Diskin SJ, Eck T, Greshock J, Mosse YP, Naylor T, Stoeckert CJ Jr, Weber BL, Maris JM, Grant GR "STAC: A method for testing the significance of DNA copy number aberrations across multiple array-CGH experiments." Genome Res. 2006 Sep;16(9):1149-58. https://doi.org/10.1101/gr.5076506
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