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mBPCR

mBPCR

mBPCR is an R tool for estimating copy number variation (CNV) using Bayesian Piecewise Constant Regression.

Topic

Genetics; Microarray experiment; Sequence analysis

Details

  • Operation: Variant detection; copy number estimation
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU GPL v2
  • Cost: Free
  • Version name: 1.38.0
  • Maturity: Stable
  • Credit: The Swiss National Science Foundation and by Oncosuisse Grant OCS 1939-08-2006.
  • Contact: rancoita.paola _at_ gmail.com
  • Collection: BioConductor

Publications

Rancoita PM, Hutter M, Bertoni F, Kwee I "Bayesian DNA copy number analysis." BMC Bioinformatics. 2009 Jan 8;10:10. https://doi.org/10.1186/1471-2105-10-10
PMID: 19133123
PMCID: PMC2674052


Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J1, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M "Orchestrating high-throughput genomic analysis with Bioconductor." Nat Methods. 2015 Feb;12(2):115-21. https://doi.org/10.1038/nmeth.3252
PMID: 25633503
PMCID: PMC4509590


Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J. "Bioconductor: open software development for computational biology and bioinformatics." Genome Biol. 2004;5(10):R80. Epub 2004 Sep 15. https://doi.org/10.1186/gb-2004-5-10-r80
PMID: 15461798
PMCID: PMC545600


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