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mBPCR is an R tool for estimating copy number variation (CNV) using Bayesian Piecewise Constant Regression.


Genetics; Microarray experiment; Sequence analysis


  • Operation: Variant detection; copy number estimation
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU GPL v2
  • Cost: Free
  • Version name: 1.38.0
  • Maturity: Stable
  • Credit: The Swiss National Science Foundation and by Oncosuisse Grant OCS 1939-08-2006.
  • Contact: rancoita.paola _at_
  • Collection: BioConductor


Rancoita PM, Hutter M, Bertoni F, Kwee I "Bayesian DNA copy number analysis." BMC Bioinformatics. 2009 Jan 8;10:10.
PMID: 19133123
PMCID: PMC2674052

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J1, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M "Orchestrating high-throughput genomic analysis with Bioconductor." Nat Methods. 2015 Feb;12(2):115-21.
PMID: 25633503
PMCID: PMC4509590

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J. "Bioconductor: open software development for computational biology and bioinformatics." Genome Biol. 2004;5(10):R80. Epub 2004 Sep 15.
PMID: 15461798
PMCID: PMC545600

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