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Genome-wide complex trait analysis. GCTA estimates the variance explained by all the SNPs on a sequence for a complex trait, instead of testing associations of each individual SNP.


Biology, Genetics, Molecular genetics, Genetic variation, DNA polymorphism


  • Operation: Analysis, Genotyping
  • Software interface: Command-line interface
  • Language: C++
  • Operating system: Linux, Microsoft Windows, Mac OS X
  • License: GNU GPL
  • Cost: -
  • Version name: src: 1.92.0beta3, Linux, Windows, Mac OS X: 1.92.0beta3
  • Credit: Jian Yang, Peter Visscher, Mike Goddard, Hong Lee, Zhili Zheng, Zhihong Zhu, Jian Zeng, Andrew Bakshi, Robert Maier.
  • Contact: -
  • Collection: -


Yang J, Lee SH, Goddard ME, Visscher PM "GCTA: a tool for genome-wide complex trait analysis." Am. J. Hum. Genet. 2011; 88(1):76-82
PMID: 21167468
PMCID: PMC3014363

Yang J, Lee SH, Goddard ME, Visscher PM "Genome-wide complex trait analysis (GCTA): methods, data analyses, and interpretations." Methods Mol. Biol. 2013
PMID: 23756893

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