Genome-wide complex trait analysis. GCTA estimates the variance explained by all the SNPs on a sequence for a complex trait, instead of testing associations of each individual SNP.
Biology, Genetics, Molecular genetics, Genetic variation, DNA polymorphism
Yang J, Lee SH, Goddard ME, Visscher PM "GCTA: a tool for genome-wide complex trait analysis." Am. J. Hum. Genet. 2011; 88(1):76-82 https://doi.org/10.1016/j.ajhg.2010.11.011
PMID: 21167468
PMCID: PMC3014363
Yang J, Lee SH, Goddard ME, Visscher PM "Genome-wide complex trait analysis (GCTA): methods, data analyses, and interpretations." Methods Mol. Biol. 2013 https://doi.org/10.1007/978-1-62703-447-0_9
PMID: 23756893
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