A web-based tool to predict the effect of amino acid mutations in protein sequences by pair-wise alignments of protein sequences in the UniProt Swiss-Prot/TrEMBL database and estimates deleteriousness utilizing a taxonomic distance of the species.
A web-based tool to predict the effect of amino acid mutations in protein sequences by pair-wise alignments of protein sequences in the UniProt Swiss-Prot/TrEMBL database and estimates deleteriousness utilizing a taxonomic distance of the species.
Cost:
Free for academic not for profit research only.
Version name:
2.0
Credit:
Matthew Jacobson, Paul Pavlidis, Erich Kuechler, Eric T.C. This work was funded by Canadian Institutes of Health Research (CIHR); Natural Sciences and Engineering Research Council of Canada (NSERC); Genome Canada and Genome BC [175REG to J.G.]; Michael Smith Foundation for Health Research (MSFHR) [CI-SCH-03020(11-1) to J.G.]. Funding for open access charge: CIHR; NSERC; Genome Canada and Genome BC [175REG to J.G.]; MSFHR [CI-SCH-03020(11-1) to J.G.].
Contact:
nmalhis at msl.ubc.ca, gsponer at msl.ubc.ca.