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MethGo

MethGo

Analysis of data from whole-genome bisulfite sequencing (WGBS) and reduced representation bisulfite sequencing (RRBS). Analyses- 1. coverage distribution of each cytosine; 2. global cytosine methylation level; 3. cytosine methylation level distribution; 4. cytosine methylation level of genomic elements; 5. chromosome-wide cytosine methylation level distribution; 6. Gene-centric cytosine methylation level; 7. cytosine methylation levels at transcription factor binding sites (TFBSs); 8. single nucleotide polymorphism (SNP) calling; 9. copy number variation (CNV).

Topic

Biology, Genetics, Molecular genetics, Genetic variation, DNA structural variation

Details

  • Operation: Sequence analysis, Nucleic acid sequence analysis , Methylation analysis, Genetic variation analysis, SNP detection, SNP calling
  • Software interface: Command-line interface
  • Language: Python
  • License: The MIT License (MIT)
  • Cost: -
  • Version name: Python 2.7
  • Credit: Liao WW, Yen MR, Ju E, Hsu FM, Lam L, Chen PY.
  • Contact: -
  • Collection: -

Publications

Liao WW, Yen MR, Ju E, Hsu FM, Lam L, Chen PY "MethGo: a comprehensive tool for analyzing whole-genome bisulfite sequencing data." BMC Genomics 2015 https://doi.org/10.1186/1471-2164-16-S12-S11
PMID: 26680022
PMCID: PMC4682368


Download and documentation




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