A tool to detect single nucleotide polymorphism (SNP) in heterogeneous virus population from Illumina sequencing data. The QQ-SNV algorithm uses a logistic regression classifier model based on quantiles of quality scores.
Genetic variation
Van der Borght K, Thys K, Wetzels Y, Clement L, Verbist B, Reumers J, van Vlijmen H, Aerssens J "QQ-SNV: single nucleotide variant detection at low frequency by comparing the quality quantiles." BMC Bioinformatics. 2015 Nov 10;16:379. https://doi.org/10.1186/s12859-015-0812-9
PMID: 26554718
PMCID: PMC4641353
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