A web tool to predict the effect of single nucleotide polymorphism (SNP) on protein function.
Biology, Genetics, DNA polymorphism
Ngak-Leng Sim Prateek Kumar Jing Hu Steven Henikoff Georg Schneider Pauline C Ng. "SIFT web server: predicting effects of amino acid substitutions on proteins." Nucleic Acids Research, Volume 40, Issue W1, July 2012, Pages W452–W457. https://doi.org/10.1093/nar/gks539
PMID: 22689647
PMCID: PMC3394338
Prateek Kumar, Steven Henikoff, Pauline C Ng. "Predicting the effects of coding non-synonymous." Nature Protocols 4, - 1073 - 1081. https://doi.org/10.1038/nprot.2009.86
PMID: 19561590
Robert Vaser, Swarnaseetha Adusumalli, Sim Ngak Leng, Mile Sikic, Pauline C Ng. "SIFT missense predictions for genomes." Nature Protocols volume 11, pages 1–9. https://doi.org/10.1038/nprot.2015.123
PMID: 26633127
Ng PC, Henikoff S. "SIFT: Predicting amino acid changes that affect protein function." Nucleic Acids Res. 2003 Jul 1;31(13):3812-4. https://doi.org/10.1093/nar/gkg509
PMID: 12824425
PMCID: PMC168916
Ng PC, Henikoff S. "Predicting deleterious amino acid substitutions." Genome Res. 2001 May;11(5):863-74. https://doi.org/10.1101/gr.176601
PMID: 11337480
PMCID: PMC311071
Ng PC, Henikoff S. "Accounting for human polymorphisms predicted to affect protein function." Genome Res. 2002 Mar;12(3):436-46. https://doi.org/10.1101/gr.212802
PMID: 11875032
PMCID: PMC155281
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