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An R package for selection of regulatory elements, single nucleotide variants (SNVs), single nucleotide polymorphisms (SNPs), and is-regulatory elements (CREs) using random forests.


Machine learning, Nucleic acids sites, features and motifs, Genetic variation


  • Operation: Variant filtering
  • Software interface: Command-line interface, R package
  • Language: R
  • Operating system: Linux, Microsoft Windows, Mac OS X
  • License: Not stated
  • Cost: Free
  • Version name: 3.3.2
  • Credit: Guilhamon P, Lupien M.
  • Contact: Joshua Mayer joshua.mayer at, Souparno Ghosh souparno.ghosh at
  • Collection: -


Guilhamon P, Lupien M "SMuRF: a novel tool to identify regulatory elements enriched for somatic point mutations." BMC Bioinformatics 2018; 19(1):454
PMID: 30477433
PMCID: PMC6258448

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