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A database for phenotyping human single nucleotide polymorphisms (SNPs).


Genotype and phenotype, Proteins, Structure prediction, Protein folding, stability and design, Protein modifications


  • Operation: Protein secondary structure prediction, Protein post-translation modification site prediction, Protein feature detection, Protein structure prediction
  • Software interface: Web user interface
  • Language: -
  • License: Not stated
  • Cost: Free
  • Version name: 4.0
  • Maturity: Mature
  • Credit: Greet De Baets, Joost Van Durme, Joke Reumers, Joost Schymkowitz, Frederic Rousseau
  • Contact:
  • Collection: -


Reumers J, Schymkowitz J, Ferkinghoff-Borg J, Stricher F, Serrano L, Rousseau F "SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs." Nucleic Acids Res. 2005; 33(Database issue):D527-32
PMID: 15608254
PMCID: PMC540040

Joke Reumers, Sebastian Maurer-Stroh, Joost Schymkowitz and Frederic Rousseau. "SNPeffect v2.0: a new step in investigating the molecular phenotypic effects of human non-synonymous SNPs." Bioinformatics. (2006),22:2183-2185.
PMID: 16809394

Reumers J, Conde L, Medina I, Maurer-Stroh S, Van Durme J, Dopazo J, Rousseau F, Schymkowitz J "Joint annotation of coding and non-coding single nucleotide polymorphisms and mutations in the SNPeffect and PupaSuite databases." Nucleic Acids Res. 2008; 36(Database issue):D825-9
PMID: 18086700
PMCID: PMC2238831

De Baets G, Van Durme J, Reumers J, Maurer-Stroh S, Vanhee P, Dopazo J, Schymkowitz J, Rousseau F "SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants." Nucleic Acids Res. 2012; 40(Database issue):D935-9
PMID: 22075996
PMCID: PMC3245173

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