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A website with tools for assignng molecular functional effects of non-synonymous single nucleotide polymorphisms (SNPs) based on structures and sequences.


Biology, Genetics, DNA polymorphism


  • Operation: Pathway or network analysis, Query and retrieval
  • Software interface: Web user interface
  • Language: -
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: Peng Yue, Eugene Melamud and John Moult
  • Contact: lray1 at
  • Collection: -


Peng Yue, Zhaolong Li, John Moult. "Loss of Protein Structure Stability as a Major Causative Factor in Monogenic Disease." J Mol Biol. 2005 Oct 21;353(2):459-73
PMID: 16169011

Peng Yue and John Moult. "Identification and Analysis of Deleterious Human SNPs." J Mol Biol. 2006 Mar 10;356(5):1263-74
PMID: 16412461

Yue P, Melamud E, Moult J "SNPs3D: candidate gene and SNP selection for association studies." BMC Bioinformatics 2006
PMID: 16551372
PMCID: PMC1435944

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