Predicts effects of single amino acid substitutions (SNPs), using neural networks. Visualizes prediction scores as a heatmap.
Biology, Genetics, DNA polymorphism
Bromberg Y, Rost B "SNAP: predict effect of non-synonymous polymorphisms on function." Nucleic Acids Res. 2007; 35(11):3823-35 https://doi.org/10.1093/nar/gkm238
PMID: 17526529
PMCID: PMC1920242
Hecht M, Bromberg Y, Rost, B. "News from the protein mutability landscape." Journal of molecular biology, 425(21), 3937-3948 https://doi.org/10.1016/j.jmb.2013.07.028
PMID: 23896297
Hecht M, Bromberg Y, Rost B "Better prediction of functional effects for sequence variants." BMC Genomics 2015 https://doi.org/10.1186/1471-2164-16-S8-S1
PMID: 26110438
PMCID: PMC4480835
If you find errors, please report here.
SECTIONS
TutorialsFind thousands of Bioinformatics and Life Science software tools and databases in the newly launched
Ads