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Predicts effects of single amino acid substitutions (SNPs), using neural networks. Visualizes prediction scores as a heatmap.


Biology, Genetics, DNA polymorphism



Bromberg Y, Rost B "SNAP: predict effect of non-synonymous polymorphisms on function." Nucleic Acids Res. 2007; 35(11):3823-35
PMID: 17526529
PMCID: PMC1920242

Hecht M, Bromberg Y, Rost, B. "News from the protein mutability landscape." Journal of molecular biology, 425(21), 3937-3948
PMID: 23896297

Hecht M, Bromberg Y, Rost B "Better prediction of functional effects for sequence variants." BMC Genomics 2015
PMID: 26110438
PMCID: PMC4480835

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