TeraPCA is a tool for principal component analysis of genomic markers in large genomes. The TeraPCA algorithm can work multi-threaded and requires only a few gigabytes of RAM. TeraPCA requires BLAS and LAPACK libraries.
Biology, Genetics, Molecular genetics, Genetic variation, DNA polymorphism
Bose A, Kalantzis V, Kontopoulou EM, Elkady M, Paschou P, Drineas P "TeraPCA: a fast and scalable software package to study genetic variation in tera-scale genotypes." Bioinformatics. 2019 Oct 1;35(19):3679-3683. https://doi.org/10.1093/bioinformatics/btz157
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