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EMMAX (Efficient Mixed-Model Association eXpedited) is a tool for testing association mapping considering the sample structure in genome-wide association studies (GWAS). The EMMAX algorithm uses a variance component approach that can analyze GWAS datasets within hours.


GWAS study


  • Operation: Genetic mapping
  • Input: PED (PLINK)
  • Output: -
  • Software interface: Command-line user interface
  • Language: C++;C
  • Operating system: Linux
  • License: Not stated
  • Cost: Free
  • Version name: beta
  • Credit: National Science Foundation (NSF), National Institutes of Health (NIH), Microsoft Research, Samsung Scholarship, National Human Genome Research Institute, National Institute for Mental Health, GlaxoSmithKline, the University of California, Los Angeles, the National Toxicology Program and National Institute of Environmental Health Sciences; Perlegen Sciences.
  • Contact: h3kang _at_ | sabatti _at_ | eeskin _at_
  • Collection: -


Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E "Variance component model to account for sample structure in genome-wide association studies." Nat Genet. 2010 Apr;42(4):348-54.
PMID: 20208533
PMCID: PMC3092069

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