EMMAX (Efficient Mixed-Model Association eXpedited) is a tool for testing association mapping considering the sample structure in genome-wide association studies (GWAS). The EMMAX algorithm uses a variance component approach that can analyze GWAS datasets within hours.
Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E "Variance component model to account for sample structure in genome-wide association studies." Nat Genet. 2010 Apr;42(4):348-54. https://doi.org/10.1038/ng.548
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