EPIQ

EPIQ is a tool to detect epistasis in quantitative GWAS. The EPIQ algorithm uses metric embedding and random projections to eliminate the need to exhaustively test all SNP pairs.

Topic

Computational biology, Molecular genetics, Genetic variation

Details

Operation: Statistical calculation
Software interface: Command-line interface
Language: C++
Operating system: Linux, Mac OS X
License: GNU GPL v2

Cost

Version name: Beta

Credit: The Edmond J. Safra Center for Bioinformatics at Tel-Aviv University, the Israel Science Foundation, National Science Foundation, the 6th Framework Program, the 7th Framework Program, RiskyCAD, the INTERREG IV Oberrhein Program, the European Regional Development Fund (ERDF) and the Wissenschaftsoffensive.
Contact: heran _at_ post.tau.ac.il
Collection: -

Publications

Arkin Y, Rahmani E, Kleber ME, Laaksonen R, März W, Halperin E "EPIQ-efficient detection of SNP-SNP epistatic interactions for quantitative traits." Bioinformatics 2014; 30(12):i19-25 https://doi.org/10.1093/bioinformatics/btu261
PMID: 24931983
PMCID: PMC4229902

Download and documentation

Source: https://github.com/yaarasegre/EPIQ
Documentation: https://github.com/yaarasegre/EPIQ/blob/
master/Arkin2014.pdf
Home page: https://github.com/yaarasegre/EPIQ

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EPIQ

EPIQ

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Download and documentation

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