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EPIQ is a tool to detect epistasis in quantitative GWAS. The EPIQ algorithm uses metric embedding and random projections to eliminate the need to exhaustively test all SNP pairs.


Computational biology, Molecular genetics, Genetic variation


  • Operation: Statistical calculation
  • Software interface: Command-line interface
  • Language: C++
  • Operating system: Linux, Mac OS X
  • License: GNU GPL v2
  • Cost: Free
  • Version name: Beta
  • Credit: The Edmond J. Safra Center for Bioinformatics at Tel-Aviv University, the Israel Science Foundation, National Science Foundation, the 6th Framework Program, the 7th Framework Program, RiskyCAD, the INTERREG IV Oberrhein Program, the European Regional Development Fund (ERDF) and the Wissenschaftsoffensive.
  • Contact: heran _at_
  • Collection: -


Arkin Y, Rahmani E, Kleber ME, Laaksonen R, März W, Halperin E "EPIQ-efficient detection of SNP-SNP epistatic interactions for quantitative traits." Bioinformatics 2014; 30(12):i19-25
PMID: 24931983
PMCID: PMC4229902

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