GDT (generalized disequilibrium test) is a tool for genome-wide association studies (GWAS). The GDT algorithm has functions for generalized family-based association tests for dichotomous traits using the genotype discrepancies of all discordant corresponding pairs in evaluating association within a family.
Genetics; GWAS study; Genotype and phenotype
Chen WM, Manichaikul A, Rich SS "A generalized family-based association test for dichotomous traits." Am. J. Hum. Genet. 2009; 85(3):364-76 https://doi.org/10.1016/j.ajhg.2009.08.003
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