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GEMMA

GEMMA

GEMMA (genome-wide efficient mixed-model association) is a tool for testing association in genome-wide association study (GWAS) data. The GEMMA algorithm computes exact Wald statistics and p-values.

Topic

Statistics and probability; Genetics; Genotype and phenotype

Details

  • Operation: Nucleic acid sequence analysis
  • Software interface: Command-line user interface
  • Language: C++
  • Operating system: Linux; Mac OS X
  • License: GNU General Public License v3
  • Cost: Free
  • Version name: 0.98.1
  • Maturity: Stable
  • Credit: The National Institutes of Health (NIH), the Wellcome Trust.
  • Contact: xz7 _at_ uchicago.edu | mstephens _at_ uchicago.edu
  • Collection: -

Publications

Zhou X, Stephens M "Genome-wide efficient mixed-model analysis for association studies." Nat. Genet. 2012; 44(7):821-4 https://doi.org/10.1038/ng.2310
PMID: 22706312
PMCID: PMC3386377


French L, Lane S, Law T, Xu L, Pavlidis P "Application and evaluation of automated semantic annotation of gene expression experiments." Bioinformatics 2009; 25(12):1543-9 https://doi.org/10.1093/bioinformatics/btp259
PMID: 19376825
PMCID: PMC2687992


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