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GISPA

GISPA

GISPA (Gene Integrated Set Profile Analysis) is a tool to determine specified gene sets with a similar molecular profile.

Topic

GWAS study; Statistics and probability

Details

  • Operation: Gene-set enrichment analysis
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU GPL v2
  • Cost: Free
  • Version name: 1.10.0
  • Maturity: Stable
  • Credit: Leukemia and Lymphoma Society Translational Research Program, Georgia Research Alliance Scientist Award, the Winship Cancer Institute of Emory University, Biostatistics and Bioinformatics Shared Resource of Winship Cancer Institute of Emory University and NIH-NCI.
  • Contact: Bhakti Dwivedi bhakti.dwivedi _at_ emory.edu
  • Collection: Bioconductor

Publications

Kowalski J, Dwivedi B, Newman S, Switchenko JM, Pauly R, Gutman DA, Arora J, Gandhi K, Ainslie K, Doho G, Qin Z, Moreno CS, Rossi MR, Vertino PM, Lonial S, Bernal-Mizrachi L, Boise LH "Gene integrated set profile analysis: a context-based approach for inferring biological endpoints." Nucleic Acids Res. 2016; 44(7):e69 https://doi.org/10.1093/nar/gkv1503
PMID: 26826710
PMCID: PMC4838358


Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J1, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M "Orchestrating high-throughput genomic analysis with Bioconductor." Nat Methods. 2015 Feb;12(2):115-21. https://doi.org/10.1038/nmeth.3252
PMID: 25633503
PMCID: PMC4509590


Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J. "Bioconductor: open software development for computational biology and bioinformatics." Genome Biol. 2004;5(10):R80. Epub 2004 Sep 15. https://doi.org/10.1186/gb-2004-5-10-r80
PMID: 15461798
PMCID: PMC545600


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