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GMDR is a tool to identify gene-gene and gene-environment Interactions for complex traits. The GMDR tool can use continuous, count, dichotomous, polytomous nominal, ordinal, survival and multivariate, and unrelated case-control, family-based and pooled unrelated and family samples, and can adjust covariates.


Comparative genomics; Epigenomics; GWAS study


  • Operation: Statistical inference
  • Software interface: Graphical user interface
  • Language: Java;Perl
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU GPL v2
  • Cost: Free
  • Version name: 1.0
  • Credit: The National Institutes of Health (NIH), National Science Foundation (NSF), the National Basic Research Programs of China, the National Natural Science Foundation.
  • Contact: hmxu _at_
  • Collection: -


Xu HM, Xu LF, Hou TT, Luo LF, Chen GB, Sun XW, Lou XY "GMDR: Versatile Software for Detecting Gene-Gene and Gene-Environ- ment Interactions Underlying Complex Traits." Curr Genomics. 2016 Oct;17(5):396-402.
PMID: 28479868
PMCID: PMC5320543

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