GWAS3D is a web-based tool for the computation of the probability of genetic variants that associate with regulatory pathways and respective diseases or traits. The GWAS3D algorithm integrates chromatin state, functional genomics, sequence motif, and conservation information with GWAS data or a variant list. See also GWAS4D server (links).
Transcription factors and regulatory sites; Molecular interactions, pathways and networks; Epigenetics; GWAS study; Sequencing
Li MJ, Wang LY, Xia Z, Sham PC, Wang J "GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications." Nucleic Acids Res. 2013; 41(Web Server issue):W150-8 https://doi.org/10.1093/nar/gkt456
PMID: 23723249
PMCID: PMC3692118
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