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GWIZ-Rscript is a tool to assess the performance of genome-wide association studies (GWAS) for the prediction of disease risk. The GWIZ-Rscript algorithm uses ROC curves and calculates the AUROC using GWAS summary-level data.


GWAS study; Genetics; Biomarkers; Pathology


  • Operation: Collapsing methods; Genotyping; Regression analysis
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: Not stated
  • Cost: Free
  • Version name: -
  • Credit: Genome Canada, Genome Alberta, the Canadian Institutes of Health Research, the Canada Foundation for Innovation, the Natural Sciences and Engineering Research Council.
  • Contact: dwishart _at_
  • Collection: -


Patron J, Serra-Cayuela A, Han B, Li C, Wishart DS "Assessing the performance of genome-wide association studies for predicting disease risk." PLoS One 14(12): e0220215.
PMID: 31805043
PMCID: PMC6894795

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