MACLEAPS is a tool to predict disease risk in genome-wide association studies (GWAS). The MACLEAPS algorithm uses support vector machines.
GWAS study; Pathology; Machine learning; Genetics
Mittag F, Büchel F, Saad M, Jahn A, Schulte C, Bochdanovits Z, Simón-Sánchez J, Nalls MA, Keller M, Hernandez DG, Gibbs JR, Lesage S, Brice A, Heutink P, Martinez M, Wood NW, Hardy J, Singleton AB, Zell A, Gasser T, Sharma M, International Parkinson’s Disease Genomics Consortium "Use of support vector machines for disease risk prediction in genome-wide association studies: concerns and opportunities." Hum. Mutat. 2012; 33(12):1708-18 https://doi.org/10.1002/humu.22161
PMID: 22777693
PMCID: PMC5968822
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