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PC-select
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PC-select

PC-select is a tool for the computation of association statistics in genome-wide association studies (GWAS). The PC-select algorithm uses a data-adaptive GRM to improve power and avoids confounding from population stratification.



PC-select

PC-select is a tool for the computation of association statistics in genome-wide association studies (GWAS). The PC-select algorithm uses a data-adaptive GRM to improve power and avoids confounding from population stratification.

Topic

GWAS study; Genetics; Population genetics; Genotype and phenotype

Details

  • Operation: Calculation
  • Software interface: Command-line user interface
  • Language: MATLAB
  • Operating system: Linux
  • License: Not stated
    • Cost: Free
  • Version name: -
  • Credit: This study makes use of data generated by the Wellcome Trust Case Control Consortium. This research was funded by National Institutes of Health grants R01 GM108348 and R01 HG006399.
  • Contact: bab _at_ mit.edu
  • Collection: -

Publications

Tucker G, Price AL, Berger B "Improving the power of GWAS and avoiding confounding from population stratification with PC-Select." Genetics 2014; 197(3):1045-9 https://doi.org/10.1534/genetics.114.164285
PMID: 24788602
PMCID: PMC4096359


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