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RAISS is a tool for the imputation of single-nucleotide polymorphisms (SNPs) in genome-wide association study (GWAS) summary data. The RAISS is suitable for multi-trait analyses.


Genetics; GWAS study; Statistics and probability


  • Operation: Statistical calculation
  • Input: TSV
  • Output: TSV
  • Software interface: Command-line user interface
  • Language: Python
  • Operating system: Linux
  • License: The MIT licence
  • Cost: Free
  • Version name: 1.0, 2.0
  • Maturity: Mature
  • Credit: National Institutes of Health (NIH)
  • Contact: Hugues Aschard hugues.aschard _at_ | Hanna Julienne hanna.julienne _at_
  • Collection: -


Julienne H, Shi H, Pasaniuc B, Aschard H "RAISS: robust and accurate imputation from summary statistics" Bioinformatics. 2019 Nov 1;35(22):4837-4839.
PMID: 31173064
PMCID: PMC6853677

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