SKAT is a tool for the evaluation of the cumulative effect of sequence variants by association tests. The SKAT algorithm combines tests of SNP sets and computes p-values and power vs. sample size to assist in experiment design.
Ionita-Laza I, Lee S, Makarov V, Buxbaum JD, Lin X "Sequence kernel association tests for the combined effect of rare and common variants." Am J Hum Genet. 2013 Jun 6;92(6):841-53. 2013 May 16. https://doi.org/10.1016/j.ajhg.2013.04.015
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