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SKAT

SKAT

SKAT is a tool for the evaluation of the cumulative effect of sequence variants by association tests. The SKAT algorithm combines tests of SNP sets and computes p-values and power vs. sample size to assist in experiment design.

Topic

GWAS study

Details

  • Operation: Mapping
  • Software interface: Command-line user interface; Library
  • Language: R
  • Operating system: Linux; Mac OS X; Microsoft Windows
  • License: GNU General Public License v>=2
  • Cost: Free
  • Version name: 1.3.2.1
  • Credit: National Science Foundation (NSF), National Institutes of Health (NIH).
  • Contact: ii2135 _at_ columbia.edu | xlin _at_ hsph.harvard.edu | ii2135 _at_ columbia.edu | xlin _at_ hsph.harvard.edu
  • Collection: -

Publications

Ionita-Laza I, Lee S, Makarov V, Buxbaum JD, Lin X "Sequence kernel association tests for the combined effect of rare and common variants." Am J Hum Genet. 2013 Jun 6;92(6):841-53. 2013 May 16. https://doi.org/10.1016/j.ajhg.2013.04.015
PMID: 23684009
PMCID: PMC3675243


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