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cit is a tool to test hypotheses mediation analysis. It uses the causal inference test (CIT) based on hypothesis testing.


Statistics and probability; Phenomics; GWAS study


  • Operation: Sequence alignment analysis (site correlation)
  • Software interface: Command-line user interface
  • Language: R
  • Operating system: Mac OS X; Microsoft Windows
  • License: Artistic-2.0
  • Cost: Free
  • Version name: 2.2
  • Maturity: Stable
  • Credit: The National Institutes of Health (NIH).
  • Contact: Joshua Millstein joshua.millstein _at_
  • Collection: -


Millstein J, Chen GK, Breton CV "cit: hypothesis testing software for mediation analysis in genomic applications." Bioinformatics. 2016 Aug 1;32(15):2364-5. Epub 2016 Mar 9.
PMID: 27153715
PMCID: PMC4965632

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